# escalation

## New phase I methods in escalation

Introducing new methods in escalation for TPI, mTPI and Neuenschwander et al.'s design for phase I trials, plus MCMC-based CRM methods.

## trialr and escalation

The trialr package, the escalation package, how they work together, and how they will grow.

## Simulation or enumeration with dose-finding designs?

Simulation is the popular approach but brute-force enumeration is more accurate and can even be quicker.

## Dose-paths in the escalation package

Enumerate every possible dose selection decision for all dose-finding models implemented in the escalation package.

## Introducing escalation

An R package to unify the interface of dose-escalation models in R. A modular approach that is scalable and extensible.